The 23-year-old midfielder has been one of the most important players in the Strasbourg team this season, making 21 appearances in Ligue 1.
But the French club are worried about receiving offers for him before the window closes on Monday as several clubs are interested in securing his services.
Atalanta have been keeping tabs on him with a view to making a move and he has also been linked with a switch to England this month.
According to French sports daily L’Equipe, Newcastle are tracking the midfielder as they look to bring in fresh reinforcements before deadline day.
Steve Bruce wants to bring in a midfielder and Sissoko is one of the players the club are considering making a move for.
They have not made any concrete offer but Strasbourg are anticipating an approach for Sissoko in the coming days.
He has a contract until 2024 with the French club and Strasbourg are likely to demand a big fee if enquiries are made.
