The French defender is set to join Bayern Munich after he worked out an agreement over a contract with the German giants.
Bayern Munich will trigger the release clause in his RB Leipzig contract soon and have him in the squad in the summer transfer window.
The 22-year-old French defender was also on the shortlist of several clubs in the Premier League, with Manchester United believed to be keen on him.
But it has been claimed that it has been months since Manchester United backed out of their race to sign the centre-back in the summer.
There are suggestions that Manchester United took a look at him and felt that his signing would not be a massive upgrade on the options they have in the squad for the price he is available at.
Manchester United killed their interest in the Frenchman as early as the start of the current season and have been looking at other targets.
Chelsea were also keen on Upamecano but were scouts were not convinced about taking him to Stamford Bridge.