The Premier League champions completed the majority of their transfer business earlier in the window but are still in the market for further signings.
Manchester City strengthened their backline by roping in left-back Sergio Gomez, but they still want defensive reinforcements.
Aymeric Laporte, Ruben Dias, John Stones and Nathan Ake form the quartet of senior centre-backs available to Manchester City boss Pep Guardiola at present.
But the Spaniard wants another centre-back option at his disposal and has identified a potential signing in the Bundesliga.
Manchester City have zeroed in on Dortmund star Akanji and are locked in talks with the German giants over a deal for him.
The Mancunians are trying to secure Akanji’s signature in a €17.5m deal and they are optimistic an agreement can be reached with Dortmund soon.
Akanji is currently in the final year of his contract at Dortmund and has not played for them so far this season, but could find himself plying his trade in the Premier League soon.