Rodgers had his best centre-backs out injured and he was forced to field a makeshift backline in the Glasgow derby on Sunday.
However, his side still beat Rangers and registered a clean sheet as the pressure piled on Michael Beale in the opposition dugout.
A section of the Celtic fans have been sceptical about Rodgers’ return due to the acrimonious way he left the club previously and the Bhoys have also not looked at their best at the start of the season.
However, McGinn believes the win over Rangers is the real start to his second stint at Celtic and could prove to be a pivotal moment.
He also feels that given the circumstances ahead of the game it is also the most important win he has enjoyed as Celtic manager.
McGinn said on the Go Radio Football Show: “It felt like the start of Brendan Rodgers’ second spell.
“It was a real ‘I am back’ moment for Brendan Rodgers.
“I said last week that I felt going into the game that if he can leave Ibrox with three points, it would be his biggest win as a Celtic manager.
“I am sure he has enjoyed victories more, but he had available and what he didn’t have available on the day and the nature of the weeks leading up to the game, it was a really significant win for him.”
Celtic will not be winning the domestic treble this season as they have been knocked out of the Scottish League Cup but are the favourites to lift the Scottish Premiership title again.