Argyle, who were in League One along with Wednesday last term, are due to welcome the Owls to Home Park in a Championship clash.
Sheffield Wednesday are already on their second manager of the season in the shape of Danny Rohl and have not won a Championship game in 12 attempts, sitting bottom.
Plymouth have won three of their matches and Cooper thinks it is vital they make Home Park advantage count against the Owls, especially as both sides are at the bottom end of the table.
“I think we have got to make the most of our home games, especially against teams that are going to be in and around us as well come April, May”, Cooper was quoted as saying by Plymouth Live.
“Every game I want to try to win, but especially at home where we know we get the backing, and then the away games see where it takes you.”
Sheffield Wednesday have not beaten Plymouth at Home Park since 2009 in the Championship and were beaten 2-1 in the fixture in League One last season.
The Owls have lost their last three away games on the spin, but Plymouth have lost their last two home matches, and the contest promises to be a frantic one with both sides aware of the importance of the points.
