Rangers are dealing with a few injury issues ahead of travelling to Pittodrie to take on the Dons, as they look to continue moving towards the title.
Ryan Jack and Kemar Roofe will not be in action and Scott Arfield is set to be out for a while after suffering an ankle injury last week.
Rangers are still favourites to beat the Dons away from home on Sunday, but Rough believes Aberdeen have the players to cause any side problems if they play at their best.
He feels the Gers can put out a real statement of intent if they beat Aberdeen on the road and prove that they are not going to suffer a meltdown like last term.
However, Rough believes if Aberdeen manage to beat Rangers, the spectre of last term’s collapse will rise again for Steven Gerrard’s side.
The former goalkeeper said on PLZ Soccer: “Aberdeen can cause anybody a problem up there if they put their mind to it, they certainly have got the players.
“It is one of those places where you would expect to get a really tough game.
“Rangers will be looking at the game as sort of matching up to the Kilmarnock game last year when it all went pear shaped for them.
“I’d think they would be saying to themselves if we get over this hurdle then that is sort of out of the way, we are not going to fall into the same trap we fell into last year and look at the score.
“That would be the motivation for this game particular because if Aberdeen were to win it people would start talking about what happened at the turn of the year.
“So, in that aspect, it’s a big game for Rangers. They will want to win it, they will want to win it comfortably.”
Rangers could extend their lead at the top of the table to 22 points if they win on Sunday, with Celtic in action on Monday.